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Scope
The main objective of the Bone and Soft Tissue Biomechanics Laboratory is to support clinicians who are treating fracture patients by providing better, more cost effective fracture treatment methods based on scientific evidence.
Using animal modeling as a primary tool, research by the investigators in the Bone and Tissue Biomechanics Laboratory is directed at quantifying the effects of mechanical stimulation (stress, motion, muscle contraction, sequential muscle compression) on rate and quality of bone and cartilage healing, and preventing and treating fracture non-union.
Research
Current projects include:
- Measurement of blood flow at the fracture site during healing period;
- Effect of amount of blood flow on rate of fracture healing;
- Improving adolescent growth plate fracture treatment method;
- Improving adolescent rotational leg deformity correction method.
Apparatus
Full scale hard and soft tissue histology facility:
- XCT 3000 pQCT
- Small animal surgery facility with vivarium
- Small bone torsion testing device
Staff
The Bone and Soft Tissue Biomechanics Laboratory is under the direction of Sang-Hyun Park, Ph.D.
Selected Publications
- Park, S.H., O'Connor, K., McKellop, H., Sarmiento, A.: The influence of active shear or compressive motion on fracture healing. J Bone and Joint Surg. 80(A) 6: 868-878, 1998
- Park, S.H., Silva, M., Bahk, W.J., McKellop, H., Lieberman, J.: Effect of repeated irrigation and debridement on fracture healing in an animal model, J. Orthop. Res. 20(6): 1197-1204, 2002
- Park, S.H., O’Connor, K. McKellop, H.: Interaction between Active Motion and Exogenous Transforming Growth Factor Beta (TGF-b1) during Tibial Fracture Repair, J Orthop Trauma 17(1): 2-10, 2003
- Park, S.H., Silva M.:Effect of pneumatic soft tissue compression of fracture healing in an animal model. J Bone Joint Surg 85A(8) 1446-1453, 2003
- Park, S.H. and Silva, M.: Neuromuscular Electrical Stimulation Enhances Fracture Healing: Results of an Animal Model. J Orthop Res 22(2) 382-387, 2004
Contact
Sang-Hyun Park, Ph.D., SPark@laoh.ucla.edu, tel: (213) 742-1443
Continue: Cartilage Cell Biology Laboratory
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Dr. Park at work
Data from a study measuring bone density
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