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Orthopaedic Hemophilia Treatment Center


For over 50 years, the Orthopaedic Hemophilia Treatment Center (OHTC) has pioneered the concept of providing a comprehensive, multidisciplinary team approach to the management of children and adults with bleeding disorders. In 1970, the Center was designated as an International Hemophilia Training Center, one of the first four in the world by the World Federation of Hemophilia.

The highly specialized and trained physicians working in the OHTC are leaders in their field, regular contributors to medical literature, actively involved in Hemophilia based research and treatment, in leadership positions in national and international Hemophilia organizations, and are invited speakers on the subject around the world.

Treatment Center - Goal and Objective
The goal of the Hemophilia Treatment Center is to provide comprehensive, multidisciplinary care for persons with congenital bleeding disorders and for the complications of those disorders, including full care for the HIV disease. The comprehensive, multidisciplinary treatment philosophy brings together hematologists, orthopaedic surgeons, physical therapists, social workers, and nurses to support patients and their families. Adults and adolescents who have acquired blood-borne infections, including chronic hepatitis and HIV infection, through prior treatment with blood products, are also treated at the Center.

The objective of the Center is the diagnosis and optimal management of bleeding disorders and their complications. Disorders treated include hemophilia A and B, von Willebrand's disease, and other inborn deficiencies of plasma clotting factors and platelets.

The staff at the Orthopaedic Hemophilia Treatment Center understand that hemophilia is a serious, chronic, life-long disorder, and patients need more than purely medical management. Bleeding can happen at any time, disrupting school or work, may cause prolonged periods of pain and disability, and decrease quality of life. To assist patients at these times, the Center's social workers and counselors work with parents to help their children develop self-esteem and manage their disorder, and provide help allowing adults to live independently. Further assistance is given to women from families affected by hemophilia who are at risk of being carriers via couseling and testing

We are the largest adult (ages 14+) Hemophilia Treatment Center in Southern California with a team of doctors, nurses, social workers, physical therapists, and pharmacists dedicated to providing treatment and care to people with Hemophilia and other bleeding and clotting disorders. 

Comprehensive, Multidisciplinary Team
  • World-renowned doctors who specialize in Hemophilia and other related bleeding and clotting disorders.
  • Nurses, social workers and physical therapists, who understand the social and physical needs of people with Hemophilia, and with many years of experience caring for people with Hemophilia and other bleeding and clotting disorders.

Customized Individual Care -- Our staff provides care and treatment according to an individual's specific needs. We tailor our services to best fit the needs of our patients and adjust treatment and care accordingly. 

Full-Service Pharmacy -- We have a full service outpatient pharmacy that specializes in factor products and their auxiliary supplies, other prescription medications, and over the counter medications. Medication and supplies can be picked up or sent overnight to your place of residence.

Approved by the State of California as a GHPP/CCS provider -- The Orthopaedic Hemophilia Treatment Center is approved by the State of California as a Genetically Handicapped Persons Program and a California Children's Services provider.

Specialized Coagulation Laboratory -- Our Coagulation Laboratory performs specialized tests on site to provide your doctors with results to make your diagnosis and treatment plans quickly. 

Supported by UCLA Health resources -- Our staff work closely with the UCLA Medical Center, the Santa Monica-UCLA Medical Center, and Orthopaedic Hospital to provide you with state-of-the-art care and referrals to top specialists for surgeries and other procedures not performed at our center.

Treatment and Services
Services include comprehensive care for patients: medical, social/psychological, and orthopaedic care, as well as diagnostic testing and counseling. We customize your treatment according to your needs including:

Diagnosis and evaluation of adult and pediatric patients suspected of having:

  • hemophilia
  • sickle cell
  • thrombosis
  • associated bleeding or clotting disorders

Treatment includes:

  • joint reconstruction
  • radiosynovectomies
  • self-infusion and prophylaxis
  • inhibitor management
  • infectious disease management of HIV, Hepatitis B, CJD, and West Nile
  • emergency management of hemophilia, sickle cell, thrombosis, and other bleeding disorders.
  • psychosocial support for family members.
  • physical therapy and rehabilitation.
  • financial counseling for patients and parents.
  • referrals to specialist.
  • education provided to patients and/or families to increase knowledge of disorder and help improve quality of life.
Additional Services


  • Education of patients, family members, teachers, employers and the community regarding bleeding and clotting disorders
  • Education of healthcare professionals regarding hemophilia, sickle cell, HIV and related disorders
  • Resident and Fellowship training in the comprehensive care of hemophilia and related disorders


  • Clotting-factor and factor-inhibitor assays, including those needed within 24 hours
  • Hepatitis and HIV screening
  • DNA analysis for carrier detection
  • Other specialized tests


  • Study of issues central to hemophilia, including inhibitor formation, induction of immune tolerance, prevention of viral infections, and promotion of joint health
  • Collection and analysis of individual patient data regarding treatment efficacy and patient morbidity and mortality
  • Assessment of the impact of psychosocial interventions on the quality of life of hemophiliacs and their families

Our multidiscipline team consists of hematologists, orthopaedists, nurses, social workers, a physical therapist, laboratory technologists, scheduling staff, and insurance staff all working together to offer a comprehensive and individualized treatment plan tailored to your needs.

The physicians are world-renowned experts in the diagnosis, treatment, and management of Hemophilia and other bleeding disorders.


Doris V. Quon, M.D., Ph.D. is board-certified in Hematology, Oncology and Internal Medicine. She first began her training at the Center in 1999, and is currently the Medical Director of the HTC. Dr. Quon has an active role in coordinating the federally funded (Region IX) hemophilia activities of the Center and is the current Medical Director of the Hemophilia Foundation of Southern California.

Victor J. Marder, M.D. is board-certified in Internal Medicine and specializes in thrombotic and hematological disorders. He has been a leader in the study of thrombosis and hemostasis for over 45 years. Dr. Marder joined the Center in 1999. He has been Chair of the Council of the International Society of Haemostasis and Thrombosis (ISTH), President of the 17th ISTH Congress in 1999, and is a recipient of the Distinguished Career Award from the ISTH.

Carol K. Kasper, M.D. is an internist with a subspecialty in hematology. She is well-known for her study of the diagnosis and treatment of hemophilia over the past 40 years. She currently tutors hematology Fellows at the Center. Dr. Kasper is an Emerita Professor of Medicine of the University of Southern California. She was the medical director of the World Federation of Hemophilia from 1994 to 2000, and has been on the Board of Directors of the National Hemophilia Foundation since 2004. Visit her website at


James V. Luck, Jr., M.D. is a board-certified orthopaedic surgeon specializing in hemophilia disorders, bone and soft tissue tumors and joint reconstruction and the current Director of Surgical Services. Dr. Luck has been actively involved with the Hemophilia Treatment Center since 1968 and has performed more reconstructive surgeries on hemophilia patients than almost any other surgeon in the world.

Mauricio Silva, M.D. is an orthopaedic surgeon specializing in hemophilia disorders, children's orthopaedics and joint reconstruction. Dr. Silva has since become a member of the World Federation of Hemophilia and sits on the Musculoskeletal Committee.


Christopher Chan, N.P. is the nurse practitioner providing coordination of care, scheduling for testing and surgeries, telephone consults and symptom management, in coordination with the clinic doctors at OHTC.

Social Workers 

Michelle Carrillo, MSW is a licensed and certified social worker providing psychosocial support and financial counseling to patients and their families.

Romana Belarde-Crespo, LCSW

Physical Therapy Team

Cindy Bailey, Ph.D, D.P.T., O.C.S., S.C.S., A.T.C., E.M.T. is a licensed and certified physical therapist provides rehabilitation and physical therapy services to improve joint range-of-motion and recovery from orthopaedic surgeries.

Scheduling Coordinators

The Coordinators schedule appointments for new and established patients. They also obtain contact and insurance information, and coordinate appointments to work with the patient's schedule.

Insurance Coordinator

The Insurance Coordinator is familiar with insurance plans such as GHPP, HMO, PPO/POS and Medical/Medicare, and provides information on insurance plan limitations on care, requirements for pre-authorization for services, patient obligations for payment and reimbursement/billing requirements.

Laboratory Technologists

Licensed and research technologists specialize in coagulation laboratory analysis, including clotting-factor and factor-inhibitor assays.

Q: Where are you located?
A: The Hemophilia Treatment Center is located in Los Angeles at the Orthopaedic Institute for Children, between the Staples Center and the University of Southern California, located at 403 West Adams Boulevard, Los Angeles, CA. We are conveniently located near the 110, 10, 101 and 5 freeways. 

Q: What are your hours and how do I get there?
A: The Center is open from 8:30 a.m. to 5:00 p.m., Monday - Friday. For after-hours or weekend care, patients may go to the Orthopaedic Institute for Children Urgent Care from 7:00 a.m. to 11:00 p.m., 7 days-a-week. The Urgent Care is located on the first floor of the same building the Hemophilia Treatment Center is located, in downtown Los Angeles and can be reached at: (213) 742-1162. Click here for map and directions.

Q: How do I make an appointment?
A: Please call (213) 742-1402 to schedule an appointment. If you are a new patient, you will be asked to provide contact information, your birth date, insurance information, some medical history and the referring physician, if applicable.

Q: What kind of insurance do you accept?
A: The Center accepts most private insurance, government insurance and cash patients in special cases. Authorization is required. Please contact (213) 742-1679 to speak with our Insurance Coordinator for more information.

Q. Do you accept GHPP and CCS?
A: Yes, we do. Our Center is one of only 12 hemophilia centers approved by the State of California for Genetically Handicapped Persons Program and California Children's Services to treat hemophilia.

Q: Do you have staff that can speak Spanish?
A: Yes, several members of our staff are fluent in Spanish. Translation services for other languages are also available.

Q: How long has the Center been open?
A: The Hemophilia Treatment Center has been open for over 35 years. Our Medical Director, Dr. Quon has been with the Center since 1999 and Dr. Kasper (Emeritus Professor) has been with the center for over 35 years.

Q: Is there a pharmacy where I can fill my prescriptions?
A: Yes, there is an outpatient pharmacy open from 8:30 a.m. - 5:00 p.m., Monday - Friday. The pharmacy provides factor products, prescription medication and over-the-counter medication.

Q: Does your Center treat Joint Problems?
A: Yes. Our Center is part of the Los Angeles Orthopaedic Medical Center and we have orthopaedic clinics twice a month. Hemophilia is characterized by bleeding into the joints and muscles due to very slow clotting of the blood. The disease is crippling. Appropriate treatment in childhood can prevent many joint problems and maintain normal mobility. Patients with established arthritis may gain relief by means of various physical therapy programs or reconstructive surgical procedures. Through the strong research commitment of our staff, new techniques for the treatment and management of hemophilia are brought into clinic use once they have been shown to be safe and effective. For example, radionuclide synovectomy is now being used for treatment of chronic synovitis in selected hemophiliacs, avoiding the need for surgery.